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The TGF-? signaling pathway is linked to the regulation of expansion and proliferation of cells as well as migration, differentiation and apoptosis. Perspective PathwaySCs elicit immunogenic responses and may go through immune surveillance in numerous immune system factors. Immunosurveillance of SCs potentiates the immune program for efficient reco
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Current studies have implicated the Hippo pathway and its transcriptional effectors YAP and TAZ as necessary for fibroblast activation and tissue fibrosis. To test the particular and enough roles for TAZ in driving autonomous fibroblast activation, we cultured NIH3T3 fibroblasts expressing a doxycycline-inducible nuclear-localized mutant of TAZ (TA